Claudin-1

Product Information
  • Cat:PA6958

  • Clone NO:YN02376m

  • Application:IHC-P

  • Positive cellular localization: Cytomembrane

  • Reactivity: Human

  • Host: Mouse

Background

Claudin-1 belongs to the Claudins protein family and is a transmembrane protein expressed in epithelial cells and pericytes. Claudin-1 is expressed in several tumors: peripheral neuroma (some types can be negative), dermatofibrosarcoma protuberans, low-grade fibromyxoid sarcoma, sclerosing fibroblastoma, fibromatosis, and nerve fiber Fibroma, schwannoma, etc. It can be combined with EMA (+) and S-100 (-) for the diagnosis of peripheral neuroma.

Pathological Antibodies