Positive cellular localization: nucleus
Androgen receptor (AR) plays an important role in the development of prostate cancer. The positive expression of AR is related to the degree of prostate cancer tissue differentiation, and the patients with AR have significant effect on anti-hormone therapy. It is mainly used to detect prostate cancer and guide the treatment. At present, it can also be used in the research of breast cancer, esophageal cancer and other malignant tumors. Androgen receptor (AR) is highly expressed in well differentiated tumors, but low or no expression in poorly differentiated tumors.
Immunohistochemistry of paraffinembedded Human prostate cancer tissue with Androgen Receptor(AR) Monoclonal Antibody