CD45RO

Background

CD45RO is expressed in most glandular cells, T cells, granulocytes, mature monocytes and some macrophages. It is a T cell marker. Studies have shown the CD45RO antibody reacts with mature activated T-cells, most thymocytes and a sub-population of resting T-cells within both CD4 and CD8 subsets. Other studies have demonstrated that CD45RO shows no reactivity with normal B-cells and B-cell lymphoma , so it can be used to differentiate T-cell lymphoma from B-cell lymphoma.