GST-π

Background

Glutathione transferase π (GST-π) is a multifunctional drug metabolism enzyme, which exists in human cytoplasm and mitochondria, mainly distributed in the middle urinary, digestive and respiratory epithelium, and mainly catalyzes the binding of GSH with various electrophilic substances to form GS-X excretion to achieve detoxification. At present, GST-π is mainly used for cell drug resistance research and is related to drug resistance such as cisplatin.