Kappa
Product Information
Cat:PA7172
Clone NO:YN02125r
Application:IHC-P
Positive cellular localization: Cytoplasm
Reactivity: Human
Host: Rabbit
Background
Kappa chain, also known as κ Light chain, immunoglobulin κ Light chain, is mainly expressed in B cells. Individual B-cells in lymphoid tissue expresses either Kappa or Lambda light chains, but never both. When κ light chain is used in combination with λ light chain, if the number of positive B cells in one light chain is much more than that of the other light chain, it is called light chain restriction, which indicates monoclonal hyperplasia and thus helping to distinguish benign and malignant lymphoid hyperplasia.
Formalin-fixed, paraffin-embedded (FFPE) Human Tonsil tissue with Kappa Monoclonal Antibody.