SALL4

Background

SALL4 gene is responsible for regulating the self-renewal of embryonic stem cells and is a key gene in many tumors. SALL4 is a kind of carcinoembryonic protein. Studies show that SALL4 is a sensitive and specific marker of seminoma and ovarian primordial germ cell tumor, and also a marker of invasive hepatocarcinoid subtype. SALL4 can be used as a potential target for targeted treatment of hepatocarcinoid.