Topoisomerase IIα Monoclonal Antibody
Positive cellular localization: Cytoplasm
Topo Ⅱ is an endonuclease and a target molecule of some tumor drugs. At the same time, it is related to signal transduction, cell proliferation and apoptosis. The higher the expression level of Topo Ⅱ, the higher the sensitivity to tumor drugs. At present, it is mostly used in the study of drug resistance of tumor.