ZAP-70
Product Information
Cat:PA6657
Clone NO:YN01716m
Application:IHC-P
Positive cellular localization: Cytoplasm
Reactivity: Human
Host: Mouse
Background
ZAP-70 is a kind of protein kinase, which is expressed in T cells and NK cells and participates in the activation of T cell receptor. The mutation of this gene will lead to severe compound immunodeficiency syndrome (SCID). The antigen is also related to the mutation of LG heavy chain gene in patients with chronic lymphocytic leukemia (CLL), disease progression and prognosis. Therefore, the expression of ZAP-70 can be used for the prognosis of CLL.
Formalin-fixed, paraffin-embedded (FFPE) Human Tonsil tissue with ZAP-70 Monoclonal Antibody.